MICROBIAL DEGRADATION OF CORRINOIDS I. Vitamin B 12
نویسندگان
چکیده
منابع مشابه
Microbial degradation of corrinoids. VI. Reduction of hydroxocobalamin by cell-free particles from Pseudomonas rubescens.
Cell-free particles from Pseudomonas rubescens have been shown to reduce hydroxocobalamin to vitamin B(12r). The particles are unable to reduce the B(12r) to B(12s). The reduction of hydroxocobalamin is dependent upon reduced nicotinamide adenine dinucleotide and is stimulated by flavin adenine dinucleotide. Cobinamide and diaquocobinamide were reduced at 25 and 10%, respectively, of the rate o...
متن کاملVitamin B-12.
V itamin B-12 is a cofactor for 2 enzymes. In the cytoplasm, methionine synthase requires vitamin B-12 in the form of methylcobalamin and catalyzes the conversion of homocysteine to methi-onine by transfer of a methyl group from methyltet-rahydrofolate. This enzyme links the methylation pathway through synthesis of the methyl donor S-adenosyl methionine and the pathway in which purine and pyrim...
متن کاملThe Vitamin B 12 Coenzyme
INTRODUCTION In 19'58 Barker and his associates l 3 recognized a new coenzyme which controlled the conversion of glutamate into ,8-methylaspartate by Clostridium tetanomorph'im. The coenzyme was shown4 to be related to ",-vitamin B12, i.e. contair ing an adenine nucleotide grouping in place of the 5,6-dimethylbe:nziminalole nucleotide of vitamin B12, although similar coenzymes containing b{ nzi...
متن کاملLongitudinal concentrations of vitamin B(12) and vitamin B(12)-binding proteins during uncomplicated pregnancy.
BACKGROUND Because reference values for vitamin B(12) concentrations and vitamin B(12)-binding capacities for pregnant women have not been established, the reference values for nonpregnant women are often applied to assess vitamin B(12) status. The aim of the present study was to describe ranges of biochemical indices of vitamin B(12) status, including red blood cell (RBC) vitamin B(12), satura...
متن کاملRole of third serum vitamin B 12 binding protein in vitamin B 12 transport.
A third vitamin B(12) binding protein present in normal serum has been shown to participate in transport of labelled vitamin B(12) absorbed from the gut. All three vitamin B(12) binding proteins in serum were labelled at the same time after oral administration of vitamin B(12), implying that "free" vitamin B(12) reached the portal blood from the gut mucosa.
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1964
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.88.3.581-585.1964